Evaluation of urine culture: common organisms and their antimicrobial susceptibility patterns in a tertiary care hospital of Peshawar
Keywords:
Anti-bacterial agents; Escherichia coli; Drug Resistance; Microbial Sensitivity Tests; Urinary Tract Infections.Abstract
Introduction: Urinary Tract Infections (UTIs) have great clinical significance because they are a major cause of morbidity and antibiotic use among older adults. Considering the high recurrence rates and emergence of antibiotic resistance in uropathogens, knowledge about the area-specific prevalence of these pathogens and their antimicrobial resistance patterns is necessary.
Objective: To document the common bacterial microorganisms causing UTI and their antimicrobial resistance patterns based on reported urine samples from a tertiary care hospital of Peshawar, KP, Pakistan.
Materials & Methods: This was an observational cross-sectional study, conducted at Rehman Medical Institute, Peshawar, on archival urine samples of UTI patients reported from January 2016 to March 2017. Antimicrobial sensitivity tests were performed according to the guidelines of Clinical and Laboratory Standards Institute (CLSI).
Results: A total of 626 samples were tested. The samples tested for urine cultures had 34.9% (n=218) males and 65.1% (n=408) females. Mean age of all subjects was 41.19 ± 27.06 years. Escherichia coli and Enterococcus were the most commonly isolated pathogens. E. coli showed highest resistance to Ampicillin and Enterococcus was highly resistant to Ciprofloxacin.
Conclusion: Antimicrobial resistance is high in urine samples from a tertiary care hospital of Peshawar, KP, and seen against drugs which are routinely prescribed to treat urinary tract infections.
