Rising Burden of Diabetes Mellitus in Pakistan: Trends, Risk Factors, and Challenges

Burden of Diabetes Mellitus in Pakistan

Authors

DOI:

https://doi.org/10.52442/jrmi.v11i3.928

Keywords:

Diabetes mellitus, Genetic Factors, Obesity, Primary Healthcare Services, Refined Carbohydrates

Abstract

Diabetes mellitus is a growing public health concern in Pakistan, with one of the highest prevalence rates of over 30.8% in 2021 globally and affecting 33 million adults. Contributing factors to this alarming rise include genetic predisposition, urbanization, unhealthy diets high in refined carbohydrates and sugars, sedentary lifestyles, and increased obesity, particularly among women and limited awareness. Pakistan faces significant healthcare challenges, that hinder effective management, such as insufficient screening, limited infrastructure and lack of specialized care in rural areas, and high treatment costs. Cultural barriers, such as resistance to dietary changes and limited physical activity for women, further impede the prevention. Urgent multi-sectorial strategies are needed to strengthen the primary healthcare services, expand public awareness campaigns, promote physical activity, improve access to medications, and support research to control diabetic epidemic and reduce its health and economic burden in Pakistan.

References

Hossain MJ, Al-Mamun M, Islam MR. Diabetes mellitus, the fastest growing global public health concern: Early detection should be focused. Health Sci Rep. Mar 2024;7(3):e2004. Doi: 10.1002/hsr2.2004.

Collaborators GBDD. Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. Jul 15 2023;402(10397):203-34. Doi: 10.1016/S0140-6736(23)01301-6.

Tremblay J, Hamet P. Environmental and genetic contributions to diabetes. Metabolism. Nov 2019;100S:153952. Doi: 10.1016/j.metabol.2019.153952.

Taimur H, Ahmad I, Khan H, et al. A scoping review of type 2 diabetes mellitus in Pakistan investigating the status of glycemic control, awareness, treatment adherence, complications and cost. Front Endocrinol (Lausanne). 2024;15:1441591. Doi: 10.3389/fendo.2024.1441591.

Magliano DJ, Boyko EJ. IDF Diabetes Atlas 10th edition scientific committee . IDF DIABETES ATLAS [Internet]. 10th edition. Brussels: International Diabetes Federation; 2021. Chapter 3, Global picture. Available from: https://www.ncbi.nlm.nih.gov/books/NBK581940/. 2021.

Sabiha B, Bhatti A, Fan KH, et al. Assessment of genetic risk of type 2 diabetes among Pakistanis based on GWAS-implicated loci. Gene. May 30 2021;783:145563. Doi: 10.1016/j.gene.2021.145563.

Hodgson S, Williamson A, Bigossi M, et al. Genetic basis of early onset and progression of type 2 diabetes in South Asians. Nat Med. Jan 2025;31(1):323-31. Doi: 10.1038/s41591-024-03317-8.

Rashid T, Afnan BH, Baloch AA, Mughal S, Hasan M, Khan MU. Dietary Patterns and Physical Activity Levels Among People With Type 2 Diabetes. Nutr Metab Insights. 2023;16:11786388231189591. Doi: 10.1177/11786388231189591.

Shapiro J, Grajower MM. The Influence of Diverse Cultures on Nutrition, Diabetes Management and Patient Education. Nutrients. Nov 2 2024;16(21). 3771 Doi: 10.3390/nu16213771.

Schulz MC, Sargis RM. Inappropriately sweet: Environmental endocrine-disrupting chemicals and the diabetes pandemic. Adv Pharmacol. 2021;92:419-56. Doi: 10.1016/bs.apha.2021.04.002.

Soomro MH, Baiz N, Huel G, et al. Exposure to heavy metals during pregnancy related to gestational diabetes mellitus in diabetes-free mothers. Sci Total Environ. Mar 15 2019;656:870-76. Doi: 10.1016/j.scitotenv.2018.11.422.

Basit A, Fawwad A, Siddiqui SA, Baqa K. Current management strategies to target the increasing incidence of diabetes within Pakistan. Diabetes Metab Syndr Obes. 2019;12:85-96. Doi:10.29392/001c.84191.

Downloads

Published

2025-08-27