Prevalence of self medication with antibiotics and knowledge about antibiotic resistance: a cross-sectional study at a medical school of Pakistan

Prevalence of self medication with antibiotics in medical students

Authors

  • Rizwan Faisal Rehman Medical College, Peshawar
  • Farooq Amir Khan Rehman Medical College, Peshawar
  • Muhammad Azam Khan Rehman Medical College, Peshawar
  • Hassaan Ahmad Rehman Medical College, Peshawar

DOI:

https://doi.org/10.52442/jrmi.v11i3.808

Keywords:

Antibiotic resistance, Medical students, Self-medication, Prescription.

Abstract

Introduction: Medical students represent a unique population due to their easier access to pharmacies and foundational medical knowledge. While their training may give them a certain degree of confidence in self-diagnosing and treating minor illnesses, this practice can lead to inappropriate drug use, and ultimately, contribute to the growing problem of antibiotic resistance.

Objective: To determine the prevalence and knowledge of medical students regarding self-medication with antibiotics and its resistance.

Materials and Methods: This descriptive type of cross-sectional study was carried out in Rehman Medical College (RMC) Peshawar, Pakistan, from January 2023 to July 2023. A self-administered questionnaire was used which included demographic data, knowledge regarding self‑medication with antibiotics and its resistance, respectively. All medical students (n=593) of RMC were included in the study. Responses of the individual participants were then compiled and analyzed using SPSS v22.

Results: The response rate was 75.2% with a mean age of 21.09±1.34 years for the participants. About 80.7% of the participants were self-medicators with Cephalosporins observed as commonly used antibiotics (21%). Male and rural students were found to be significantly high self-medicators compared to their counterparts (p<0.05). A negative correlation of age and professional year was observed to the prevalence of antibiotic use. Most of the students (78.2%) knew about antibiotic resistance. The overall knowledge of students regarding antibiotic resistance was satisfactory.

Conclusion: This study revealed that self-medication was widely practiced among medical students despite having good knowledge of antibiotic resistance. Thus, it is time to implement strict bylaws to limit the sale of antibiotics without a physician’s prescription.

References

Self‑Medication ‑ World Health Organization; 2019. Available online: http:// apps.who.int/medicinedocs/en/d/Jwhozip32e/3.2.html. [Assessed 19 July 2022].

Sachdev C, Anjankar A, Agrawal J. Self-Medication with Antibiotics: An element increasing resistance. Cureus. 2022;29;14(10): e30844. Doi: 10.7759/cureus.30844.

Abduelkarem AR, Othman AM, Abuelkhair ZM, Ghazal MM, Alzouobi SB, El Zowalaty ME. Prevalence of self-medication with antibiotics among residents in United Arab Emirates. Infect Drug Resist. 2019;12: 3445-3453. Doi: 10.2147/IDR.S224720.

Tohan MM, Ahmed F, Juie IJ, Kabir A, Howlader MH, Rahman MA. Knowledge attitude and convenience on self-medication practices among university students in Bangladesh exploration using structural equation modeling approach. Sci Rep. 2024;12;14(1):10837. Doi: 10.1038/s41598-024-60931-9.

Janssen J, Afari-Asiedu S, Monnier A, Abdulai MA, Tawiah T, Wertheim H et al. Exploring the economic impact of inappropriate antibiotic use: the case of upper respiratory tract infections in Ghana. Antimicrob Resist Infect Control. 2022 Apr 1;11(1):53. Doi:10.1186/s13756-022-01096-w.

Rijal KR, Banjara MR, Dhungel B, Kafle S, Gautam K, Ghimire B, et al. Use of antimicrobials and antimicrobial resistance in Nepal: A nationwide survey. Sci. Rep. 2021; 11:11554. Doi: 10.1038/s41598-021-90812-4.

Saleem Z, Hassali MA, Godman B, Fatima M, Ahmad Z, Sajid A, Rehman IU, Nadeem MU, Javaid Z, Malik M, Hussain A. Sale of WHO AWaRe groups antibiotics without a prescription in Pakistan: a simulated client study. J Pharm Policy Pract. 2020; 13:26. Doi: 10.1186/s40545-020-00233-3.

Sharma N, Jain M, Sharma P, Jain C, Bansal A, Sharma L, et al. Prevalence of self‑medication of antibiotics among 2nd‑year medical students and their knowledge about antibiotic resistance. Int. J. Acad Med. 2020; 6(3):203-08. Doi: 10.4103/IJAM.IJAM_13_20.

Faisal R, Shah SFA, Hussain M. Potential use of azithromycin alone and in combination with ivermectin in fighting against the symptoms of COVID-19. Professional Med J 2021; 28 (5): 737-41. Doi: 10.29309/TPMJ/2021.28.05.5867.

Faisal R, Popalzai AJ, Sultana U, Abdullah Z. Class attendance of Pharmacology students of Rehman Medical College as a determinant of academic performance. JRMI. 2017;3(2-4):11-5.

Faisal R, Shinwari L, Hussain SS. Academic performance of male in comparison with female undergraduate medical students in Pharmacology examinations. J Pak Med Assoc. 2017; 67 (2): 204-08. Doi: 10.53350/pjmhs2115112917.

Limwado GD, Aron MB, Mpinga K, Phiri H, Chibvunde S, Banda C, et al. Prevalence of antibiotic self-medication and knowledge of antimicrobial resistance among community members in Neno District rural Malawi: A cross-sectional study. IJID. 2024; 13: 100444. Doi: 10.1016/j.ijregi.2024.100444.

Behzadifar M, Behzadifar M, Aryankhesal A, Ravaghi H, Baradaran HR, Sajadi HS, et al. Prevalence of self-medication in university students: systematic review and meta-analysis. East Mediterr Health J. 2020;23;26(7):846-57. Doi: 10.26719/emhj.20.052

Albusalih FA, Naqvi AA, Ahmad R, Ahmad N. Prevalence of self-medication among students of pharmacy and medicine colleges of a public sector university in Dammam city, Saudi Arabia. Pharm (Basel). 2017;5(3):51. Doi: 10.3390/pharmacy5030051.

Kanneppady SS, Oo AM, Lwin OM, Ahmed Al‑Abed AA, Kanneppady SK. Knowledge, attitude, and awareness of antibiotic resistance among medical students. Arch Med Health Sci. 2019; 7: 57‑60. Doi: 10.4103/amhs.amhs_104_18.

Okedo-Alex I, Madubueze UC, Umeokonkwo CD, Oka OU, Adeke AS, Okeke KC. Knowledge of antibiotic use and resistance among students at a medical school in Nigeria. Malawi Med J. 2019;31(2):133-137. Doi: 10.4314/mmj.v31i2.5.

Baddal B, Lajunen TJ, Sullman MJM. Knowledge, attitudes and behaviours regarding antibiotics use among Cypriot university students: a multi-disciplinary survey. BMC Med Educ. 2022;22(1):847. Doi: 10.1186/s12909-022-03853-2.

Alghadeer S, Aljuaydi K, Babelghaith S, Alhammad A, Alarifi MN. Self-medication with antibiotics in Saudi Arabia. Saudi Pharm JSPJ Off Publ Saudi Pharm Soc. 2018;26(5):719–24. Doi: 10.1016/j.jsps.2018.02.018.

Rathod P, Sharma S, Ukey U, Sonpimpale B, Ughade S, Narlawar U et al. Prevalence, Pattern, and Reasons for Self-Medication: A Community-Based Cross-Sectional Study from Central India. Cureus. 2023;15(1): e33917. Doi: 10.7759/cureus.33917.

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Published

2025-08-27